Letrozole (trade name Femara) is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.
Alias: Femara, Letrozole, TROZET
CAS :112809-51-5
MF: C17H11N5
MW: 285.3
Character: White crystalline powder.
Manufacturer : Yuanyang
Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane
Usage: Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from Letrozole include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.
1). Letrozole is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women.
2). Letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene (Clomid) and less chance of multiple gestation. A Canadian study presented at the American Society of Reproductive Medicine 2005 Conference suggested that letrozole may increase the risk of birth defects. A more detailed ovulation induction follow-up study found that letrozole, compared with a control group of clomiphene, had significantly lower congenital malformations and chromosomal abnormalities at an overall rate of 2.4% (1.2% major malformations) compared with clomiphene 4.8% (3.0% major malformations). Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.
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1). Femara (letrozole) is used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years. It is a non-steroidal aromatase inhibitor (lowers estrogen production). This medication is available in generic form.
2). The recommended dose of Femara is one 2.5 mg tablet administered once a day, without regard to meals. Other drugs may interact with Femara. Tell your doctor all prescription and over-the-counter medications and supplements you use. Femara must not be used during pregnancy. It may harm a fetus. Femara is used mainly in women after menopause. If you have recently gone through menopause, discuss birth control with your doctor. Do not use birth control containing estrogen. It is unknown if this drug passes into breast milk and may harm a nursing infant. Breast-feeding while using this drug is not recommended.
As we recommend Letrozole primarily as an on-cycle side-effect preventer most will find a dosing of 0.5-1mg every other day to be perfect and generally all the Letrozole they need to get the job done. If you are ultra-sensitive to side-effects or preparing for a bodybuilding contest 1mg every day may be in your future but this is not advised for far extended periods of time; most competitive bodybuilders will however find such dosing welcomed for approximately 10 days before a contest.
For the individual who has a Gynecomastia flare up, in order to combat this problem, as discussed Letro may be able to reverse the symptoms if it is caught early enough. In this case a dosing of 2.5mg per day for approximately 2-3 weeks may be warranted; however, once the symptoms clear you will need to cut back to a more standard 1mg per day dose in order to remain in healthy working function. It is important to note, if you take a large dose of Letrozole to combat early Gynecomastia and it does not clear the symptoms in a few weeks you’re either very sensitive to Gyno or the problem has set in for too long. If this is the case there isn’t a lot you can do, as Gyno will not go away on its own. For this individual we are afraid his only hope will to have the Gynecomastia surgically removed.
Product name | Letrozole |
Other name | Femara, Letrozole, TROZET |
CAS register number | 112809-51-5 |
Molecular formula | C17H11N5 |
Molecular weight | 285.3 |
Molecular structure | |
Assay | 98% |
Appearance | White crystalline powder |
Package | 1kg/aluminium foil bag or as required |
Usage | can be used as pharmaceutical material |
Minimum order quantity | 10g |
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